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NFE2L1 antibody

Cat.#: 113146

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Product Information

  • Product Name
    NFE2L1 antibody
  • Documents
  • Description
    NFE2L1 Rabbit Polyclonal antibody. Positive WB detected in mouse skeletal muscle tissue, Fetal mouse bone, HeLa cells, HepG2 cells, Jurkat cells, K-562 cells. Positive IP detected in mouse skeletal muscle tissue. Observed molecular weight by Western-blot: 65 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    FLJ00380 antibody; HBZ17 antibody; LCR F1 antibody; LOCus control region factor 1 antibody; NF E2 related factor 1 antibody; NFE2 related factor 1 antibody; NFE2L1 antibody; NRF1 antibody; TCF 11 antibody; TCF11 antibody; Transcription factor 11 antibody; Transcription factor HBZ17 antibody; Transcription factor LCR F1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of NFE2L1 recombinant protein (Accession Number: NM_001330262). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IP: 1:200-1:2000

  • Validations

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:113146(NFE2L1 antibody) at dilution of 1:500

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:113146(NFE2L1 antibody) at dilution of 1:500

    IP Result of anti-NFE2L1 (IP:Catalog No:113146, 4ug; Detection:Catalog No:113146 1:500) with mouse skeletal muscle tissue lysate 2200ug.

    IP Result of anti-NFE2L1 (IP:Catalog No:113146, 4ug; Detection:Catalog No:113146 1:500) with mouse skeletal muscle tissue lysate 2200ug.

  • Background
    NFE2L1, also named as HBZ17, NRF1, TCF11 and LCR-F1, belongs to the bZIP family and CNC subfamily. It activates erythroid-specific, globin gene expression. NFE2L1 is involved in mediating ascorbic acid-induced osterix expression and osteoblast differentiation via binding to the antioxidant response element of the osterix promoter. NFE2L1, produced by osteoblasts, is involved in regulating osterix expression, osteoblast differentiation, and bone formation. (PMID:19887580). This antibody is a rabbit polyclonal antibody raised against a region of human NFE2L1.
  • References
    • Kim J, Xing W, Wergedal J, Chan JY, Mohan S. Targeted disruption of nuclear factor erythroid-derived 2-like 1 in osteoblasts reduces bone size and bone formation in mice. Physiological genomics. 40(2):100-10. 2010.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"