NDUFS7 antibody

Cat.#: 113085

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Product Information

  • Product Name
    NDUFS7 antibody
  • Documents
  • Description
    NDUFS7 Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, K-562 cells. Positive IHC detected in human liver tissue. Positive IF detected in Hela cells. Observed molecular weight by Western-blot: 20kd
  • Tested applications
    ELISA, WB, IHC, IF
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    CI 20KD antibody; Complex I 20kD antibody; FLJ45860 antibody; FLJ46880 antibody; MY017 antibody; NDUFS7 antibody; PSST antibody; PSST subunit antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of NDUFS7 recombinant protein (Accession Number: NM_024407). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:1000-1:10000

    IHC: 1:20-1:200

    IF: 1:10-1:100

  • Validations

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:113085(NDUFS7 antibody) at dilution of 1:500

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:113085(NDUFS7 antibody) at dilution of 1:500

    Immunohistochemical of paraffin-embedded human liver using Catalog No:113085(NDUFS7 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human liver using Catalog No:113085(NDUFS7 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human liver using Catalog No:113085(NDUFS7 antibody) at dilution of 1:100 (under 40x lens)

    Immunohistochemical of paraffin-embedded human liver using Catalog No:113085(NDUFS7 antibody) at dilution of 1:100 (under 40x lens)

    Immunofluorescent analysis of Hela cells, using NDUFS7 antibody Catalog No:113085 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

    Immunofluorescent analysis of Hela cells, using NDUFS7 antibody Catalog No:113085 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

  • Background
    NDUFS7(NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial) protein is one of the most conserved subunits of mitochondrial respiratory chain complex I and plays a central role in the interaction with the electron acceptor ubiquinone and in the proton-translocating mechanism(PMID:15269216).Defects in NDUFS7 are a cause of Leigh syndrome (LS) and mitochondrial complex I deficiency (MT-C1D).
  • References
    • Frykman S, Teranishi Y, Hur JY. Identification of two novel synaptic γ-secretase associated proteins that affect amyloid β-peptide levels without altering Notch processing. Neurochemistry international. 61(1):108-18. 2012.
    • Inoue M, Hur JY, Kihara T. Human brain proteins showing neuron-specific interactions with γ-secretase. The FEBS journal. 282(14):2587-99. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"