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Product Name
NDUFS6 antibody
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Description
NDUFS6 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue. Positive WB detected in human heart tissue, human liver tissue, rat liver tissue. Observed molecular weight by Western-blot: 13 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CI 13kD A antibody; Complex I 13kD A antibody; NDUFS6 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of NDUFS6 recombinant protein (Accession Number: NM_004553). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:113084(NDUFS6 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:113084(NDUFS6 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:113084(NDUFS6 antibody) at dilution of 1:100 (under 40x lens)
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Background
NDUFS6(NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial) is also named as CI-13kD-A, NADH-ubiquinone oxidoreductase 13 kDa-A subunit and belongs to the complex I NDUFS6 subunit family.It is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
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References
- Sun S, Han Y, Liu J. Trichostatin A targets the mitochondrial respiratory chain, increasing mitochondrial reactive oxygen species production to trigger apoptosis in human breast cancer cells. PloS one. 9(3):e91610. 2014.
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