Napsin A antibody

Napsin A antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Napsin A Mouse Monoclonal antibody. Positive IHC detected in human lung cancer tissue, human kidney tissue, human lung tissue, rat lung tissue. Positive IF detected in HUVEC cells. Observed molecular weight by Western-blot: 45 kDa

ELISA, IHC, IF

Human,Mouse; other species not tested.

Asp 4 antibody; ASP4 antibody; Aspartyl protease 4 antibody; KAP antibody; Kdap antibody; NAP1 antibody; NAPA antibody; NAPSA antibody; Napsin 1 antibody; Napsin A antibody; napsin A aspartic peptidase antibody; Pronapsin A antibody; SNAPA antibody; TA01/TA02 antibody

Mouse IgG1

This antibody was obtained by immunization of Napsin A recombinant protein (Accession Number: NM_004851). Purification method: Protein G purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Napsin is found in two isoforms, napsin A and B, with highly homologous nucleotide sequences (91.2%). Napsin A appears to be a functional proteinase, predominantly expressed in lung and kidney. Napsin B is transcribed exclusively in cells related to the immune system and lacks an in-frame stop codon and is believed to be a pseudogene.(PMID:12698189). Napsin A is superior to TTF-1 in distinguishing primary lung ACA from other carcinomas (except kidney), particularly primary lung small cell carcinoma, and primary thyroid carcinoma.(PMID:22288963).

• Yuan J, Jiang B, Zhang A. Accelerated hepatocellular carcinoma development in CUL4B transgenic mice. Oncotarget. 6(17):15209-21. 2015.