MUTYH antibody

MUTYH antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

MUTYH Rabbit Polyclonal antibody. Positive WB detected in K-562 cells, HeLa cells, Raji cells. Observed molecular weight by Western-blot: 53kd,65kd

ELISA, WB

Human,Mouse,Rat; other species not tested.

hMYH antibody; MutY homolog antibody; mutY homolog (E. coli) antibody; MUTYH antibody; MYH antibody

Rabbit IgG

This antibody was obtained by immunization of MUTYH recombinant protein (Accession Number: NM_001293190). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

MUTYH(MutY homolog) is also named as MYH and belongs to the Nth/MutY family. The gene enconde an A/G-specific adenine DNA glycosylase that it is involved in oxidative DNA damage repair and initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities(PMID:10684930). Defects in MUTYH are a cause of familial adenomatous polyposis type 2 (FAP2) and gastric cancer (GASC). It has 6 isoforms produced by alternative splicing with the molecular weight between 57 kDa and 60 kDa.