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Product Name
MUC16,CA125 antibody
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Description
MUC16,CA125 Mouse Monoclonal antibody. Positive IHC detected in human ovary tumor tissue.
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Tested applications
ELISA, IHC
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Species reactivity
Human,Mouse; other species not tested.
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Alternative names
CA 125 antibody; CA125 antibody; FLJ14303 antibody; MUC 16 antibody; MUC16 antibody; Mucin 16 antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_024690). Purification method: Protein G purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:107433(MUC16,CA125 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:107433(MUC16,CA125 antibody) at dilution of 1:50 (under 40x lens)
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Background
MUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators. The antibody recognizes the C-term of MUC16.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"