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mu Crystallin antibody

Cat.#: 112886

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Product Information

  • Product Name
    mu Crystallin antibody
  • Documents
  • Description
    mu Crystallin Rabbit Polyclonal antibody. Positive IHC detected in human gliomas tissue. Positive WB detected in Y79 cells, human heart tissue, human kidney tissue. Observed molecular weight by Western-blot: 34kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    CRYM antibody; crystallin antibody; DFNA40 antibody; mu Crystallin antibody; Mu crystallin homolog antibody; THBP antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of mu Crystallin recombinant protein (Accession Number: NM_001376256). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:1000-1:10000

    IHC: 1:20-1:200

  • Validations

    Y79 cells were subjected to SDS PAGE followed by western blot with Catalog No:112886(CRYM antibody) at dilution of 1:400

    Y79 cells were subjected to SDS PAGE followed by western blot with Catalog No:112886(CRYM antibody) at dilution of 1:400

    Immunohistochemical of paraffin-embedded human gliomas using Catalog No:112886(CRYM antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human gliomas using Catalog No:112886(CRYM antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human gliomas using Catalog No:112886(CRYM antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human gliomas using Catalog No:112886(CRYM antibody) at dilution of 1:50 (under 40x lens)

  • Background
    mu Crystallin(thiomorpholine-carboxylate dehydrogenase) is also named as THBP, CRYM, ketimine reductase and belongs to the ornithine cyclodeaminase family. This protein catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). It is also involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptor.
  • References
    • Ishido Y, Luo Y, Yoshihara A. Follicular thyroglobulin enhances gene expression necessary for thyroid hormone secretion. Endocrine journal. 62(11):1007-15. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"