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Product Name
MMP21 antibody
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Description
MMP21 Rabbit Polyclonal antibody. Positive IHC detected in human skin cancer tissue, human colon cancer tissue. Positive IF detected in L02 cells. Positive WB detected in mouse liver tissue, L02 cells. Observed molecular weight by Western-blot: 67 kDa
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Tested applications
ELISA, WB, IHC, IF
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
matrix metallopeptidase 21 antibody; Matrix metalloproteinase 21 antibody; MMP 21 antibody; MMP21 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_147191). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:20-1:200
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Validations
mouse liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:112702(MMP21 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human skin cancer tissue slide using Catalog No:112702(MMP21 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human skin cancer tissue slide using Catalog No:112702(MMP21 Antibody) at dilution of 1:50 (under 40x lens)
Immunofluorescent analysis of L02 cells using Catalog No:112702(MMP21 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
MMP21 belongs to the peptidase M10A family. It may have an important and specific function in tumor progression and embryogenesis. It cleaves alpha-1-antitrypsin. The proenzyme without the signal peptide has a calculated molecular mass of 62 kD; following activation by furin, the processed enzyme has a calculated molecular mass of 49 kD(PMID:12617721),and MMP21 protein was detected in fetal neuroectoderm, in placenta, and in leukocytes(OMIM).This antibody is specific to MMP21.
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