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Product Name
LYAR antibody
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Description
LYAR Rabbit Polyclonal antibody. Positive WB detected in A431 cells, HeLa cells, K-562 cells, mouse testis tissue. Observed molecular weight by Western-blot: 45 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
FLJ20425 antibody; LYAR antibody; ZLYAR antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of LYAR recombinant protein (Accession Number: XM_011513506). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:112405(LYAR Antibody) at dilution of 1:1000
A431 cells were subjected to SDS PAGE followed by western blot with Catalog No:112405(LYAR Antibody) at dilution of 1:1000
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Background
LYAR also named as ZLYAR or Cell growth regulating nucleolar protein is 379 amino acid protein, which contains 2 C2H2-type zinc fingers. LYAR is expressed at at high levels in immature spermatocytes, early embryos and in fetal liver and thymus ,with low expression in kidney and spleen, LYAR may function as a novel nucleolar oncoprotein to regulate cell growth. It is suggested that LYAR participates in regulating the stability of C23, a protein that is critical for maintaining the self-renewal and differentiation of embryonic stem cells.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"