LGALS3BP antibody

LGALS3BP antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

LGALS3BP Mouse Monoclonal antibody. Positive IHC detected in human breast cancer tissue, human skin cancer tissue. Positive WB detected in human blood tissue. Positive IP detected in human plasma tissue. Observed molecular weight by Western-blot: 90 kDa

ELISA, WB, IHC, IP

Human; other species not tested.

90K antibody; BTBD17B antibody; Galectin 3 binding protein antibody; LGALS3BP antibody; M2BP antibody; Mac 2 binding protein antibody; MAC 2 BP antibody; MAC2BP antibody; Tumor assOCiated antigen 90K antibody

Mouse IgG2b

This antibody was obtained by immunization of LGALS3BP recombinant protein (Accession Number: NM_005567). Purification method: Caprylic acid/ammonium sulfate precipitation.

Monoclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP is a widely expressed, secreted galectin. It has been found elevated in the serum of patients with various types of breast, lung, colorectal, ovary, and endometrial cancer, and in those infected by the human immunodeficiency virus (HIV). High expression levels of LGALS3BP are associated with a shorter survival, the occurrence of metastasis or a reduced response to chemotherapy. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Immunoblotting showed that LGALS3BP is likely contained in breast milk, serum, semen, saliva, urine, and tears.