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KIR3DL1 antibody

Cat.#: 112062

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Product Information

  • Product Name
    KIR3DL1 antibody
  • Documents
  • Description
    KIR3DL1 Rabbit Polyclonal antibody. Positive FC detected in Jurkat cells. Positive WB detected in human liver tissue. Observed molecular weight by Western-blot: 49 kDa
  • Tested applications
    ELISA, WB, FC
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    CD158E antibody; CD158E1 antibody; KIR antibody; KIR3DL1 antibody; MHC class I NK cell receptor antibody; NKAT 3 antibody; NKAT3 antibody; NKB1 antibody; NKB1B antibody; p70 NK receptor CL 2/CL 11 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of KIR3DL1 recombinant protein (Accession Number: NM_013289). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

  • Validations

    human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:112062(KIR3DL1 antibody) at dilution of 1:500

    human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:112062(KIR3DL1 antibody) at dilution of 1:500

    1X10^6 Jurkat cells were stained with 0.2ug KIR3DL1 antibody (Catalog No:112062, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1000.

    1X10^6 Jurkat cells were stained with 0.2ug KIR3DL1 antibody (Catalog No:112062, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1000.

  • Background
    Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR3DL1 is a receptor on natural killer (NK) cells for HLA Bw4 allele. It inhibits the activity of NK cells thus preventing cell lysis. KIR3DL1 and KIR3DS1 are highly homologous. This antibody is raised against 22-344 amino acids of human KIR3DL1 and recognizes both KIR3DL1 (49 kDa) and KIR3DS1 (43 kDa).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"