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Product Name
KALRN antibody
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Description
KALRN Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, human kidney tissue, mouse colon tissue. Observed molecular weight by Western-blot: 200kd
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
DUET antibody; duo antibody; FLJ16443 antibody; HAPIP antibody; Kalirin antibody; kalirin antibody; RhoGEF kinase antibody; KALRN antibody; Protein Duo antibody; TRAD antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_007064). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:111907(KALRN antibody) at dilution of 1:500
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Background
KALRN, also named as DUET, DUO, HAPIP and TRAD, belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. KALRN promotes the exchange of GDP by GTP. KALRN activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. KALRN induces lamellipodia independent of its GEF activity. The antibody can recognize isoform1 and isoform2 of KALRN.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"