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Product Name
JP45/JSRP1 antibody
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Description
JP45/JSRP1 Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue. Positive WB detected in human skeletal muscle tissue. Observed molecular weight by Western-blot: 30kd
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human; other species not tested.
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Alternative names
FLJ32416 antibody; JP 45 antibody; JP45 antibody; JP45/JSRP1 antibody; JSRP1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of JP45/JSRP1 recombinant protein (Accession Number: NM_144616). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:111895(JP45; JSRP1 antibody) at dilution of 1:50 (under 10x lens)
human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:111895(JP45; JSRP1 Antibody) at dilution of 1:600
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Background
JSRP1 (Junctional sarcoplasmic reticulum protein 1), also known as JP-45, is an integral protein of the junctional face membrane of the skeletal muscle sarcoplasmic reticulum (SR), and interacts with calsequestrin and the skeletal-muscle dihydropyridine receptor Cav1. JP-45 is an important protein for functional expression of voltage-dependent calcium channels. Involvement of JP-45 in the molecular mechanism underlying skeletal muscle excitation-contraction coupling has been reported. Although the predicated molecular weight of JP-45 is 36 kDa, it appears a 45-kDa band in western blotting in most cases.
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