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Product Name
Human ILKAP (His Tag) recombinant protein
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Description
Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation.
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Protein name
Integrin-linked kinase-associated serine/threonine phosphatase 2C
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Protein short names
0710007A14RIK; 1600009O09RIK; ILKAP3; MGC4846; ILKAP; ILKAP2; DKFZP434J2031; FLJ10181; PP2C-DELTA
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Uniprot ID
Q9H0C8
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Gene Name
ILKAP
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human ILKAP (Q9H0C8) (Met 1-His 392) was expressed, with a C-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The recombinant human ILKAP comprises 403 amino acids with a predicted molecular mass of 44.3 kDa. The apparent molecular mass of rh ILKAP is approximately 46 kDa in SDS-PAGE under reducing conditions.
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Purity
> 92 % as determined by SDS-PAGE
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Validations
Human ILKAP Protein (His Tag) SDS-PAGE
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