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Product Name
ING1-specific antibody
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Description
ING1-specific Rabbit Polyclonal antibody. Positive IP detected in mouse heart tissue. Positive WB detected in human heart tissue. Observed molecular weight by Western-blot: 30 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
ING1 antibody; Inhibitor of growth protein 1 antibody; p24ING1c antibody; p33 antibody; p33ING1 antibody; p33ING1b antibody; p47 antibody; p47ING1a antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_198218). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
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Validations
human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:111791(ING1-specific antibody) at dilution of 1:300
IP Result of anti-ING1-specific (IP:Catalog No:111791, 2ug; Detection:Catalog No:111791 1:300) with mouse heart tissue lysate 4000ug.
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Background
Members of inhibitor of growth (ING) family function in inhibiting cell growth and inducing apoptosis. They are sequence homologous proteins. ING1 is the first identified one, interacting with TP53 and is a component of the p53 signaling pathway. Multiple alternatively spliced transcript variants encoding distinct isoforms of ING1 have been reported. This antibody recognizes all 24/33/47kd isoforms of ING1, but will not bind ING2, 3 or 4.
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