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Product Name
IL21R antibody
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Description
IL21R Mouse Monoclonal antibody. Positive IHC detected in human tonsillitis tissue. Positive WB detected in K-562 cells, Jurkat cells. Observed molecular weight by Western-blot: 65 kDa
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human; other species not tested.
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Alternative names
CD360 antibody; IL 21 receptor antibody; IL 21R antibody; IL21R antibody; interleukin 21 receptor antibody; NILR antibody; Novel interleukin receptor antibody
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Isotype
Mouse IgG2b
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Preparation
This antibody was obtained by immunization of IL21R recombinant protein (Accession Number: NM_181078). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:50-1:200
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Validations
K-562 cells were subjected to SDS PAGE followed by western blot with Catalog No:107392(IL21R Antibody) at dilution of 1:1500
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using (IL21R Antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using (IL21R Antibody) at dilution of 1:100 (under 40x lens)
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Background
IL21R, a receptor for interleukin-21, belongs to the type I cytokine receptor family. IL21R has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"