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Product Name
IKBKB antibody
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Description
IKBKB Rabbit Polyclonal antibody. Positive IHC detected in human pancreas tissue. Positive IF detected in DU 145 cells. Positive WB detected in mouse testis tissue. Observed molecular weight by Western-blot: 85 kDa
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Tested applications
ELISA, WB, IHC, IF
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
FLJ40509 antibody; I kappa B kinase 2 antibody; I kappa B kinase beta antibody; IKBKB antibody; IKK B antibody; IKK beta antibody; IKK2 antibody; IKKB antibody; NFKBIKB antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_001556). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:20-1:200
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Validations
mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:111644(IKBKB antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human pancreas slide using Catalog No:111644(IKBKB Antibody) at dilution of 1:50
Immunohistochemistry of paraffin-embedded human pancreas slide using Catalog No:111644(IKBKB Antibody) at dilution of 1:50
Immunofluorescent analysis of (-20oc Ethanol) fixed DU 145 cells using Catalog No:111644(IKBKB Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
IKBKB, also named as NFKBIKB, IKK2 and IKKB, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and I-kappa-B kinase subfamily. IKBKB acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. It also phosphorylates NCOA3. The antibody is specific to IKBKB.
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