ICOS antibody

ICOS antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

ICOS Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells, HL-60 cells. Observed molecular weight by Western-blot: 28 kDa, 45-50 kDa

ELISA, WB

Human; other species not tested.

AILIM antibody; CD278 antibody; ICOS antibody; inducible T cell co stimulator antibody; Inducible T cell costimulator antibody

Rabbit IgG

This antibody was obtained by immunization of ICOS recombinant protein (Accession Number: NM_012092). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Inducible T cell co-stimulator (ICOS) is related to the CD28 superfamily and is highly expressed on activated T cells as well as regulatory T cells and is crucial for the survival and function of T cells, Th2 cell differentiation and for lung inflammatory responses. Binding ICOS to ICOS-ligand (ICOS-L) activates a cascade of intracellular signaling molecules that prevent apoptosis and lead to the production of cytokines such as IL-4 and IL-13. Catalog#13338-1-AP recognises two band of 25-30 kDa and 45-50 kDa, and the additional 45-50 kDa band may be due to glycosylation.