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Product Name
HURP antibody
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Description
HURP Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, HeLa cells. Observed molecular weight by Western-blot: 95kd
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
DAP 5 antibody; Discs large homolog 7 antibody; DLG7 antibody; DLGAP5 antibody; Hepatoma up regulated protein antibody; HURP antibody; KIAA0008 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of HURP recombinant protein (Accession Number: XM_017021840). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:111726(DLGAP5 antibody) at dilution of 1:500
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Background
DLGAP5, also named as DAP 5 or DLG7, is a kinetochore protein that stabilizes microtubules in vicinity of chromosomes. DLG7 controls spindle dynamics, promotes interkinetochore tension and efficient kinetochore capture. DGL7 is a part of Ran-dependent complex. Expression of DGL7 is found in cancer and stem cells. DLGAP5 contributes to hepatocellular carcinoma tumorigenesis by promoting cell proliferation (PMID: 24324629).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"