Human SNX18 Recombinant protein (GST tag)

Human SNX18 Recombinant protein (GST tag)

• DataSheet
• Material Safety Data Sheets (MSDS)

Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane. {PubMed:18411244, PubMed:20427313, PubMed:21048941, PubMed:22718350}.

Sorting nexin-18

SH3PXD3B; SNAG1

Q96RF0

SNX18; SH3PXD3B; SNAG1

E. coli

A DNA sequence encoding the human SNX18 (XP_047272635.1) 55-284 aa was fused with the N-terminal GST tag

Human

Not tested.