Human S100A7/PSOR1/S100A7C recombinant protein

Cat.#: 518898

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Product Information

  • Product Name
    Human S100A7/PSOR1/S100A7C recombinant protein
  • Documents
  • Description
    S100A7 is a 11-12 kDa member of the S100 family of EF hand calcium binding proteins. Human S100A7 shares 32% amino acid sequence identity with mouse S100A7A, the closest related protein in mouse. It is acetylated at the N-terminus and binds both calcium and zinc ions. S100A7 is up-regulated in keratinocytes of psoriasis and atopic dermatitis lesions, as well as in epithelial cells of the tongue, eye, and female genital tract. Its up-regulation can be induced by bacterial exposure, inflammatory cytokines, or epidermal barrier disruption. S100A7 supports epithelial integrity through killing E. coli by sequestration of zinc and through inducing the up-regulation of tight junction proteins. The interaction of S100A7 with RAGE promotes the migration of immune cells and the infiltration of macrophages into tumor sites.
  • Protein name
    S100 calcium binding protein A7(S100A7)
  • Protein short names
    PSOR1; S100A7C
  • Uniprot ID
    P31151
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human S100A7/PSOR1/S100A7C Met1-Gln101 is expressed.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human S100A7/PSOR1/S100A7C recombinant protein

    Human S100A7/PSOR1/S100A7C recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"