Human POLR3F Recombinant protein (His tag)

Cat.#: 511407

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Product Information

  • Product Name
    Human POLR3F Recombinant protein (His tag)
  • Documents
  • Description
    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway. {PubMed:19609254, PubMed:19631370}.
  • Protein name
    DNA-directed RNA polymerase III subunit RPC6
  • Uniprot ID
    Q9H1D9
  • Gene Name
    POLR3F
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human POLR3F (NP_006457.2) 1-316 aa was fused with the polyhistidine tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human POLR3F(Full length) SDS-PAGE

    Recombinant human POLR3F(Full length) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"