Human MIF/GLIF/MMIF recombinant protein

Cat.#: 518559

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Product Information

  • Product Name
    Human MIF/GLIF/MMIF recombinant protein
  • Documents
  • Description
    Human MIF is a 12.5 kDa, 115 amino acid (aa) nonglycosylated polypeptide that is synthesized without asignal sequence .Secretion occurs nonclassically via an ABCA1 transporter.Pro-inflammatory cytokine.Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites ofinflammation suggests a role as mediator in regulating the function of acrophages in host defense.Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase anddopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clearwhether the tautomerase activity has any physiological relevance, and whether it is important for cytokineactivity.
  • Protein name
    macrophage migration inhibitory factor (glycosylation-inhibiting factor)(MIF)
  • Protein short names
    GLIF; MMIF
  • Uniprot ID
    P14174
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human MIF/GLIF/MMIF Met1-Ala115 is expressed.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human MIF/GLIF/MMIF recombinant protein

    Human MIF/GLIF/MMIF recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"