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Product Name
Human KCNJ10 Recombinant protein (His tag)
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Description
May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity).
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Protein name
ATP-sensitive inward rectifier potassium channel 10
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Uniprot ID
B2R604
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Gene Name
KCNJ10
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human KCNJ10 (NP_002232.2) 177-379 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human KCNJ10 SDS-PAGE
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