Human FKBP3/FKBP25 (His tag) recombinant protein

Cat.#: 519688

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Product Information

  • Product Name
    Human FKBP3/FKBP25 (His tag) recombinant protein
  • Documents
  • Description
    FKBP3 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
  • Protein name
    FK506 binding protein 3(FKBP3)
  • Protein short names
    FKBP25
  • Uniprot ID
    Q00688
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human FKBP3/FKBP25 Met1-Asp224 is expressed with a 6His tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human FKBP3/FKBP25 (His tag) recombinant protein

    Human FKBP3/FKBP25 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"