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Product Name
Human FBXL15 Recombinant protein (His tag)
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Description
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2. {PubMed:21572392}.
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Protein name
F-box/LRR-repeat protein 15
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Protein short names
FBXO37
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Uniprot ID
Q9H469
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Gene Name
FBXL15; FBXO37
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human FBXL15 (XP_054222687.1) 92-387 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human FBXL15(Full length) SDS-PAGE
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