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Product Name
Human ESR1/ESR/NR3A1 (His tag) recombinant protein
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Description
Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but they also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
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Protein name
estrogen receptor 1(ESR1)
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Protein short names
ESR; NR3A1
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Uniprot ID
P03372
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human ESR1/ESR/NR3A1 Met1-Gln116 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human ESR1/ESR/NR3A1 (His tag) recombinant protein
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