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Human DIS3L Recombinant protein (His tag)

Cat.#: 507228

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Special Price 294.7 USD

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Product Information

  • Product Name
    Human DIS3L Recombinant protein (His tag)
  • Documents
  • Description
    Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. {PubMed:20531386, PubMed:20531389}.
  • Protein name
    DIS3-like exonuclease 1
  • Protein short names
    DIS3L1; KIAA1955
  • Uniprot ID
    Q8TF46
  • Gene Name
    DIS3L; DIS3L1; KIAA1955
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human DIS3L (NP_001137160.1) 893-1054 aa was fused with the polyhistidine tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human DIS3L SDS-PAGE

    Recombinant human DIS3L SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"