Human CCL17/TARC (His Tag) recombinant protein

Cat.#: 503630

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Product Information

  • Product Name
    Human CCL17/TARC (His Tag) recombinant protein
  • Documents
  • Description
    Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine(TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the chemokine receptor CCR4.
  • Protein name
    C-C motif chemokine 17
  • Protein short names
    SCYA17; MGC138271; CCL17; SCYA17L; ABCD-2; A-152E5.3; TARC; MGC138273
  • Uniprot ID
    Q92583
  • Gene Name
    CCL17; SCYA17; TARC
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the full length of human CCL17 (Q92583-1) (Met 1-Ser 94) was expressed, fused with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human CCL17 consists of 81 amino acids and predicts a molecular mass of 9.5 kDa. It migrates as an approximately 12 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 94 % as determined by SDS-PAGE
  • Validations

    Human CCL17 / TARC / SCYA17 Protein (His Tag) SDS-PAGE

    Human CCL17 / TARC / SCYA17 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"