Human Carbonic Anhydrase IV / Car4 / CA4 (His Tag) recombinant protein

Cat.#: 503745

Size:

Special Price 317.7 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Human Carbonic Anhydrase IV / Car4 / CA4 (His Tag) recombinant protein
  • Documents
  • Description
    The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase IV (CAIV) is a membrane-associated enzyme anchored to plasma membrane surfaces by a phosphatidylinositol glycan linkage. CAIV is a high-activity isozyme in CO2 hydration comparable to that of CAII. Furthermore, CAIV is more active in HCO3- dehydration than is CAII. However, the esterase activity of CAIV is decreased 150-fold compared to CAII.
  • Protein name
    Carbonic anhydrase 4
  • Protein short names
    CARBONIC ANHYDRASE IV; CAIV; CA IV; CA4; CA-IV; RP17; CAR4; AW456718; RP23-167D6.1
  • Uniprot ID
    P22748
  • Gene Name
    CA4
  • Source/Expression Host
    CHO Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human CA4 (NP_000708.1) (Met1-Lys283) without the pro peptide was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human CA4 consists of 276 amino acids after removal of the signal peptide and has a predicted molecular mass of 31.7 kDa. In SDS-PAGE under reducing conditions, rh CA4 migrates as approximately 34 and 19 kDa band.
  • Purity
    (48.3+49.3) % as determined by SDS-PAGE
  • Validations

    Human Carbonic Anhydrase IV / CA4 Protein (His Tag) SDS-PAGE

    Human Carbonic Anhydrase IV / CA4 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"