Human AKR1C4/CHDR (His tag) recombinant protein

Cat.#: 519045

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Product Information

  • Product Name
    Human AKR1C4/CHDR (His tag) recombinant protein
  • Documents
  • Description
    Aldo-Keto Reductase 1C4/AKR1C4 is a member of the aldo/keto reductase family that consists of more than 40 known enzymes and proteins. AKR1C4 has highly expressed in Liver. It can catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-α-Androstan-3-α,17-β-diol (3-α-diol). In addition, AKR1C4 also has some 20-α-Hydroxysteroid Dehydrogenase activity.
  • Protein name
    aldo-keto reductase family 1 member C4(AKR1C4)
  • Protein short names
    CHDR
  • Uniprot ID
    P17516
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human AKR1C4/CHDR Met1-Tyr323 is expressed with a 6His tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human AKR1C4/CHDR (His tag) recombinant protein

    Human AKR1C4/CHDR (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"