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Product Name
Human PGD2 / PGDS (His Tag) recombinant protein
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Description
Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.
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Protein name
Hematopoietic prostaglandin D synthase
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Protein short names
GLUTATHIONE S-TRANSFERASE SIGMA; PTGDS2; GLUTATHIONE S-TRANSFERASE; GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE; H-PGDS; HEMATOPOIETIC PROSTAGLANDIN D2 SYNTHASE; GST CLASS-SIGMA; GLUTATHIONE-DEPENDENT PGD SYNTHASE; GSTS; PROSTAGLANDIN D2 SYNTHASE 2; PGD2; GLUTATHIONE-DEPENDENT PGD SYNTHETASE; GSTS1; GSTS1-1; HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE; PGDS; PROSTAGLANDIN-H2 D-ISOMERASE; HPGDS; HEMATOPOIETIC
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Uniprot ID
O60760
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Gene Name
HPGDS; GSTS; PGDS; PTGDS2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human PGDS (O60760) (Met1-Leu199) was expressed with a polyhistide tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human PGDS consists of 205 amino acids and predicts a molecular mass of 24.2 KDa. It migrates as an approximately 25-29 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human PGD2 / PGDS / HPGDS Protein (His Tag) SDS-PAGE
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