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Product Name
HAS3 antibody
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Description
HAS3 Rabbit Polyclonal antibody. Positive WB detected in L02 cells, mouse liver tissue. Observed molecular weight by Western-blot: 63kd
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
HA synthase 3 antibody; HAS3 antibody; hyaluronan synthase 3 antibody; Hyaluronate synthase 3 antibody; Hyaluronic acid synthase 3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of HAS3 recombinant protein (Accession Number: NM_138612). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
L02 cells were subjected to SDS PAGE followed by western blot with Catalog No:111259(HAS3 antibody) at dilution of 1:1000
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Background
HAS3(hyaluronan synthase 3) belongs to the NodC/HAS family, which are widely expressed in human tissues and appear to function in embryogenesis, wound healing and other processes associated with cellular proliferation and migration(PMID:14566823). HAS3 is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. It may play a role in the progression of colon cancer and, as such, may provide novel targets for diagnostic and therapeutic interventions(PMID:14566823). It has 2 isoforms produced by alternative splicing and the protein has a glycosylation site.
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