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Product Name
GSTZ1 antibody
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Description
GSTZ1 Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue. Observed molecular weight by Western-blot: 25-30kd
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
glutathione transferase zeta 1 antibody; GSTZ1 antibody; GSTZ1 1 antibody; MAAI antibody; MAI antibody; Maleylacetoacetate isomerase antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of GSTZ1 recombinant protein (Accession Number: NM_001363703). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
mouse liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:111195(GSTZ1 antibody) at dilution of 1:800
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Background
Glutathione transferase zeta 1(GSTZ1) catalyzes the biotransformation of a range of α-haloacids, including dichloroacetic acid (DCA), and the penultimate step in the tyrosine degradation pathway. GSTZ1 is preferentially expressed in hepatocytes and renal proximal tubule cells where phenylalanine and tyrosine are catabolized(PMID: 16550164). This protein has 3 isoforms produced by alternative splicing.
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References
- Rojanathammanee L, Rakoczy S, Brown-Borg HM. Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice. The journals of gerontology. Series A, Biological sciences and medical sciences. 69(10):1199-211. 2014.
- Rojanathammanee L, Rakoczy S, Kopchick J, Brown-Borg HM. Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice. Age (Dordrecht, Netherlands). 36(4):9687. 2014.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"