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Product Name
GRWD1 antibody
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Description
GRWD1 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue. Positive WB detected in HEK-293 cells, PC-3 cells, SKOV-3 cells. Observed molecular weight by Western-blot: 49kd
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
GRWD antibody; GRWD1 antibody; KIAA1942 antibody; RRB1 antibody; WDR28 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of GRWD1 recombinant protein (Accession Number: NM_031485). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:111163(GRWD1 Antibody) at dilution of 1:600
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:111163(GRWD1 antibody) at dilution of 1:100 (under 25x lens)
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Background
WD-repeat proteins are a class of functionally divergent molecules that cooperate with other proteins to regulate cellular processes. WD-repeat proteins have been implicated in a variety of cellular functions that are mostly regulatory in nature, including cytoskeleton organization, vesicular fusion, pre-mRNA splicing, and cell cycle regulation. WD-repeat-containing protein designated glutamate-rich WD repeat (GRWD1) is a component of the 50S and 80S preribosomal complexes and plays a role in ribosome biogenesis and during myeloid differentiation its levels are regulated. [PMID:15885502]
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