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GRK2 antibody

Cat.#: 111212

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Product Information

  • Product Name
    GRK2 antibody
  • Documents
  • Description
    GRK2 Rabbit Polyclonal antibody. Positive IP detected in HL-60 cells. Positive WB detected in Jurkat cells, HL-60 cells. Positive FC detected in HeLa cells. Positive IHC detected in human lymphoma tissue. Observed molecular weight by Western-blot: 80 kDa
  • Tested applications
    ELISA, WB, IHC, FC, IP
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    ADRBK1 antibody; BARK antibody; BARK1 antibody; Beta ARK 1 antibody; BETA ARK1 antibody; FLJ16718 antibody; GRK2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of GRK2 recombinant protein (Accession Number: NM_001619). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:111212(ADRBK1 antibody) at dilution of 1:1000

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:111212(ADRBK1 antibody) at dilution of 1:1000

    Immunohistochemical of paraffin-embedded human lymphoma using Catalog No:111212(ADRBK1 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human lymphoma using Catalog No:111212(ADRBK1 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human lymphoma using Catalog No:111212(ADRBK1 antibody) at dilution of 1:100 (under 40x lens)

    Immunohistochemical of paraffin-embedded human lymphoma using Catalog No:111212(ADRBK1 antibody) at dilution of 1:100 (under 40x lens)

    IP Result of anti-ADRBK1 (IP:Catalog No:111212, 4ug; Detection:Catalog No:111212 1:1000) with HL-60 cells lysate 3040ug.

    IP Result of anti-ADRBK1 (IP:Catalog No:111212, 4ug; Detection:Catalog No:111212 1:1000) with HL-60 cells lysate 3040ug.

    1X10^6 HeLa cells were stained with 0.2ug ADRBK1 antibody (Catalog No:111212, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1000.

    1X10^6 HeLa cells were stained with 0.2ug ADRBK1 antibody (Catalog No:111212, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1000.

  • Background
    ADRBK1 represents adrenergic, beta, receptor kinase 1
  • References
    • Zhang C, Chen X, Li Y. si-RNA-Mediated Silencing of ADRBK1 Gene Attenuates Breast Cancer Cell Proliferation. Cancer biotherapy & radiopharmaceuticals. 29(8):303-9. 2014.
    • Yang F, Yu X, Liu C. Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR. Nature communications. 6:8202. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"