GPAA1 antibody

GPAA1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

GPAA1 Rabbit Polyclonal antibody. Positive WB detected in HepG2 cells, mouse brain tissue. Observed molecular weight by Western-blot: 60-68 kDa

ELISA, WB

Human,Mouse,Rat; other species not tested.

GAA1 antibody; GAA1 protein homolog antibody; GPAA1 antibody; hGAA1 antibody

Rabbit IgG

This antibody was obtained by immunization of GPAA1 recombinant protein (Accession Number: NM_003801). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

GPAA1(Glycosylphosphatidylinositol anchor attachment 1 protein) is also named as GAA1. It is the most conspicuously hydrophobic of the known subunits of GPIT, and it may play a key role in substrate recognition. It is predicted to be a multispanning membrane protein of 67 kDa with seven transmembrane (TM) domains, a large lumenal domain between the first two TM segments, and a cytoplasmically oriented N terminus bearing a potential ER retrieval signal in the form of a diarginine motif(PMID:12052837). It has 2 isoforms produced by alternative splicing and the full length protein has 2 glycosylation sites. This antibody is specific to GPAA1.

• Nagpal JK, Dasgupta S, Jadallah S. Profiling the expression pattern of GPI transamidase complex subunits in human cancer. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 21(8):979-91. 2008.