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Product Name
GNPDA1 antibody
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Description
GNPDA1 Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue. Positive WB detected in K-562 cells, HeLa cells, human brain tissue, rat kidney tissue. Observed molecular weight by Western-blot: 33 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
GlcN6P deaminase 1 antibody; GNPDA antibody; GNPDA 1 antibody; GNPDA1 antibody; GNPI antibody; GPI antibody; HLN antibody; KIAA0060 antibody; Oscillin antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of GNPDA1 recombinant protein (Accession Number: XM_047416582). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
K-562 cells were subjected to SDS PAGE followed by western blot with Catalog No:111008(GNPDA1 antibody) at dilution of 1:400
Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:111008(GNPDA1 antibody) at dilution of 1:50 (under 10x lens)
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Background
GNPDA1(glucosamine-6-phosphate isomerase 1) is also named as GNPI, HLN, KIAA0060 and belongs to the glucosamine/galactosamine-6-phosphate isomerase family. It catalyzes the reversible conversion of D-glucosamine-6-phosphate (GlcN6P) into D-fructose-6-phosphate (Fru6P) and ammonium(PMID:12965206). It may be playing an essential role for egg activation and early embryo development. GNPI is expressed as a 33-kD cytosolic protein in various cell lines(PMID: 9714720).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"