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Product Name
GJB6 antibody
- Documents
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Description
GJB6 Rabbit Polyclonal antibody. Positive IHC detected in human oesophagus tissue, human skin cancer tissue.
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Tested applications
ELISA, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
Connexin 30 antibody; CX30 antibody; DFNA3 antibody; DFNA3B antibody; DFNB1B antibody; ED2 antibody; EDH antibody; Gap junction beta 6 protein antibody; GJB6 antibody; HED antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of GJB6 recombinant protein (Accession Number: NM_001110221). Purification method: Antigen Affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IHC: 1:20-1:200
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Validations
Immunohistochemistry of paraffin-embedded human oesophagus tissue slide using Catalog No:110985(GJB6 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human oesophagus tissue slide using Catalog No:110985(GJB6 Antibody) at dilution of 1:50 (under 40x lens)
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Background
Gap junctions form conduits between adjacent cells that are composed of connexin protein subunits and provide direct intercellular communication pathways allowing rapid exchange of ions and metabolites (PMID: 12126230; 15094343). Connexins are four-pass transmembrane proteins with amino- and carboxy-terminal regions facing the cytoplasm. A connexon is composed of a hexamer of connexins. GJB6 (gap junction beta-6 protein, also known as connexin-30) is a member of the connexin family of proteins. GJB6 is a component of the gap junction networks of the cochlea.
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