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Galectin-1 antibody

Cat.#: 110839

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Product Information

  • Product Name
    Galectin-1 antibody
  • Documents
  • Description
    Galectin-1 Rabbit Polyclonal antibody. Positive WB detected in human liver tissue, human heart tissue. Positive IHC detected in human colon cancer tissue, human lung cancer tissue. Observed molecular weight by Western-blot: 15 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    14 kDa laminin binding protein antibody; 14 kDa lectin antibody; DKFZp686E23103 antibody; Gal 1 antibody; GAL1 antibody; Galaptin antibody; Galectin 1 antibody; Galectin-1 antibody; HBL antibody; HLBP14 antibody; HPL antibody; Lactose binding lectin 1 antibody; LGALS1 antibody; S Lac lectin 1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Galectin-1 recombinant protein (Accession Number: NM_002305). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:110839(GAL1,LGALS1 antibody) at dilution of 1:500

    human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:110839(GAL1,LGALS1 antibody) at dilution of 1:500

    Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:110839(GAL1,LGALS1 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:110839(GAL1,LGALS1 antibody) at dilution of 1:100 (under 10x lens)

  • Background
    Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for β-galactose-containing oligosac-charides (PMID: 8063692). Galectin-1 contains one carbohydrate recognition domain (CRD) and occurs as a monomer as well as a non-covalent homodimer (PMID: 16840800). It is differentially expressed by various normal and pathological tissues. Galectin-1 is a multifunctional protein that is involved in cell adhesion, migration, proliferation, apoptosis, inflammation, tumour transformation and growth (PMID:15785741).
  • References
    • Li S, Li X, Wang Y, Yang J, Chen Z, Shan S. Global secretome characterization of A549 human alveolar epithelial carcinoma cells during Mycoplasma pneumoniae infection. BMC microbiology. 14:27. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"