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Product Name
GADD45G antibody
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Description
GADD45G Rabbit Polyclonal antibody. Positive WB detected in UV treated HeLa cells, human placenta tissue. Observed molecular weight by Western-blot: 17kd
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
CR6 antibody; DDIT 2 antibody; DDIT2 antibody; GADD45G antibody; GADD45gamma antibody; GRP17 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of GADD45G recombinant protein (Accession Number: NM_006705). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
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Validations
UV treated HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:110821(GADD45G Antibody) at dilution of 1:300
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Background
GADD45G, also named as CR6, DDIT2 and GRP17, is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
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References
- Bardag-Gorce F, Dedes J, French BA, Oliva JV, Li J, French SW. Mallory body formation is associated with epigenetic phenotypic change in hepatocytes in vivo. Experimental and molecular pathology. 83(2):160-8. 2007.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"