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Product Name
FYTTD1 antibody
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Description
FYTTD1 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells. Observed molecular weight by Western-blot: 50 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
DKFZp761B1514 antibody; FYTTD1 antibody; Protein 40 2 3 antibody; UAP56 interacting factor antibody; UIF antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of FYTTD1 recombinant protein (Accession Number: NM_032288). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:110759(FYTTD1 Antibody) at dilution of 1:300
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Background
FYTTD1 also termed as UAP56 interacting factor or UIF is a 318 amino acid protein, which belongs to the UIF family. FYTTD1 localizes to nucleus and is required for mRNA export from nucleus to cytoplasm. Functioning as an adaptor, FYTTD1 utilizes the BAT1/DDX39-TAP pathway, which is essential for efficient mRNA export and nuclear pore delivery. FYTTD1 interacts with SSRP1, a protein that is necessary for its recruitment of mRNAs, in addition to a mutually exclusive interaction with BAT1/DDX39 and TAP. The molecular weight of post-translation modified FYTTD1 is observed 50 kDa.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"