FXYD2 antibody

FXYD2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

FXYD2 Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue. Positive WB detected in HEK-293 cells, human kidney tissue, human liver tissue, human skeletal muscle tissue, mouse skeletal muscle tissue. Observed molecular weight by Western-blot: 7 kDa

ELISA, WB, IHC

Human,Mouse,Rat; other species not tested.

ATP1C antibody; ATP1G1 antibody; FXYD2 antibody; HOMG2 antibody; Sodium pump gamma chain antibody

Rabbit IgG

This antibody was obtained by immunization of FXYD2 recombinant protein (Accession Number: NM_001680). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

FXYD2 (FXYD domain-containing ion transport regulator 2), also known as the gamma-subunit of the NaK-ATPase, belongs to the FXYD family which has been proposed to be the regulators of Na, K-ATPase function by lowering affinities of the system for potassium and sodium. The expression of FXYD2 is most abundant in kidney, while it is also detected in several other tissues like placenta, pancreas, and dorsal root ganglia (DRGs). Three splice variants of FXYD2 have been reported in mouse kidney, namely FXYD2 γa, -γb,and -γc. FXYD2 γa has been identified as a pancreatic beta cell-specific biomarker. This antibody can recognize all three isoforms of FXYD2.

• Lu CP, Polak L, Rocha AS. Identification of stem cell populations in sweat glands and ducts reveals roles in homeostasis and wound repair. Cell. 150(1):136-50. 2012.