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FLNB antibody

Cat.#: 110690

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Product Information

  • Product Name
    FLNB antibody
  • Documents
  • Description
    FLNB Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive WB detected in HeLa cells, NIH/3T3 cells. Observed molecular weight by Western-blot: 250-278kd
  • Tested applications
    ELISA, WB, IF
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    ABP 278 antibody; ABP 280 homolog antibody; Actin binding like protein antibody; AOI antibody; Beta filamin antibody; DKFZp686A1668 antibody; DKFZp686O033 antibody; FH1 antibody; Filamin 3 antibody; Filamin B antibody; Filamin homolog 1 antibody; FLN B antibody; FLN1L antibody; FLN3 antibody; FLNB antibody; LRS1 antibody; SCT antibody; TABP antibody; TAP antibody; Thyroid autoantigen antibody; Truncated ABP antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_001457). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IF: 1:10-1:100

  • Validations

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:110690(FLNB antibody) at dilution of 1:300

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:110690(FLNB antibody) at dilution of 1:300

    Immunofluorescent analysis of HepG2 cells, using FLNB antibody Catalog No:110690 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

    Immunofluorescent analysis of HepG2 cells, using FLNB antibody Catalog No:110690 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

  • Background
    FLNB, also named as FLN1L, FLN3, TABP, TAP and Fh1, belongs to the filamin family. FLNB connects cell membrane constituents to the actin cytoskeleton. It may promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. It is an anchors various transmembrane proteins to the actin cytoskeleton. Interaction with FLNA, FLNB may allow neuroblast migration from the ventricular zone into the cortical plate. Various interactions and localizations of isoforms affect myotube morphology and myogenesis. The antibody is specific to FLNB. It can recognize isoform1,2,3,6,7 of FLNB. It has no cross reaction to FLNA and FLNC.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"