FKBP2 antibody

Cat.#: 107216

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Product Information

  • Product Name
    FKBP2 antibody
  • Documents
  • Description
    FKBP2 Mouse Monoclonal antibody. Positive IHC detected in human prostate cancer tissue. Positive WB detected in Human cerebellum, human brain tissue. Observed molecular weight by Western-blot: 16 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    13 kDa FK506 binding protein antibody; 13 kDa FKBP antibody; FK506 binding protein 2 antibody; FK506 binding protein 2 antibody; 13kDa antibody; FKBP 13 antibody; FKBP 2 antibody; FKBP13 antibody; FKBP2 antibody; Immunophilin FKBP13 antibody; PPIase antibody; PPIase FKBP2 antibody; Rotamase antibody
  • Isotype
    Mouse IgG1
  • Preparation
    This antibody was obtained by immunization of FKBP2 recombinant protein (Accession Number: NM_001370363). Purification method: Protein G purified.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    human cerebellum tissue were subjected to SDS PAGE followed by western blot with Catalog No:107216(FKBP2 antibody) at dilution of 1:500

    human cerebellum tissue were subjected to SDS PAGE followed by western blot with Catalog No:107216(FKBP2 antibody) at dilution of 1:500

    Immunohistochemistry of paraffin-embedded human prostate cancer slide using Catalog No:107216(FKBP2 Antibody) at dilution of 1:50

    Immunohistochemistry of paraffin-embedded human prostate cancer slide using Catalog No:107216(FKBP2 Antibody) at dilution of 1:50

    Immunohistochemistry of paraffin-embedded human prostate cancer slide using Catalog No:107216(FKBP2 Antibody) at dilution of 1:50

    Immunohistochemistry of paraffin-embedded human prostate cancer slide using Catalog No:107216(FKBP2 Antibody) at dilution of 1:50

  • Background
    FKBP2 is also named as FKBP13 and belongs to the FKBP-type PPIase family. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. FKBP2 has a 21-amino acid signal peptide and appears to be membrane-associated(PMID:1713687). It is localized to the lumen of the endoplasmic reticulum (ER). FKBP12 and FKBP13 are highly similar proteins, of molecular masses 12 kDa and 13 kDa respectively, with approx.43 % amino acid identity. The strong homology between FKBP12 and FKBP13 suggests that they may share similar biological functions, although, apart from rotamase activity, details relating to the function of either protein are scant(PMID:8373365).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"