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Product Name
FKBP14 antibody
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Description
FKBP14 Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, HeLa cells, human brain tissue. Observed molecular weight by Western-blot: 28 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
22 kDa FK506 binding protein antibody; 22 kDa FKBP antibody; FK506 binding protein 14 antibody; FKBP 14 antibody; FKBP 22 antibody; FKBP14 antibody; FKBP22 antibody; FLJ20731 antibody; PPIase FKBP14 antibody; Rotamase antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of FKBP14 recombinant protein (Accession Number: NM_017946). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:110670(FKBP14 antibody) at dilution of 1:500
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Background
FKBP14, also named as FKBP22, belongs to the family of FK506-binding peptidyl-prolyl cis-trans isomerases (PPIases). PPIases accelerate the folding of proteins during protein synthesis. FKBP14 is localized in the endoplasmic reticulum (ER) and that deficiency of FKBP14 leads to enlarged ER cisterns in dermal fibroblasts in vivo. FKBP14 is about 22kd.
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References
- Baumann M, Giunta C, Krabichler B. Mutations in FKBP14 cause a variant of Ehlers-Danlos syndrome with progressive kyphoscoliosis, myopathy, and hearing loss. American journal of human genetics. 90(2):201-16. 2012.
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