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Product Name
Mouse FGF18 (His Tag) recombinant protein
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Description
Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation (By similarity).
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Protein name
Fibroblast growth factor 18
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Protein short names
ZFGF5; UNQ420/PRO856; FGF-18; RP23-413O19.3; FGF18; D130055P09RIK
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Uniprot ID
O89101
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Gene Name
Fgf18
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse FGF18 (NP_032031.1) (Met 1-Gly 207) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse FGF18 comprises 191 amino acids and has a predicted molecular mass of 22.5 kDa. As a result of glycosylation, it migrates as an approximately 30-35 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
1. Measured by its binding ability in a functional ELISA.
2. Immobilized mouse FGF18 (Cat:501491) at 10 μg/mL (100 μl/well) can bind Rat FGFR4 (Cat:500770), The EC50 of Rat FGFR4 (Cat:500770) is 0.44 μg/mL. -
Validations
Mouse FGF18 / FGF-18 Protein (His Tag) SDS-PAGE
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