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Product Name
fibrillin 2-Specific antibody
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Description
fibrillin 2-Specific Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, HepG2 cells, L02 cells, mouse lung tissue. Positive IHC detected in human placenta tissue. Observed molecular weight by Western-blot: 290 kDa,160 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CCA antibody; DA9 antibody; FBN2 antibody; fibrillin 2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_001999). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:50-1:500
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Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:110655(FBN2-Specific antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human placenta tissue slide using Catalog No:110655(FBN2-Specific Antibody) at dilution of 1:100 (under 10x lens).
Immunohistochemistry of paraffin-embedded human placenta tissue slide using Catalog No:110655(FBN2-Specific Antibody) at dilution of 1:100 (under 40x lens).
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Background
FBN2 belongs to the fibrillin family. Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils which occur either in association with elastin or in elastin-free bundles. Fibrillin-2-containing microfibrils regulate the early process of elastic fiber assembly. Defects in FBN2 are the cause of congenital contractural arachnodactyly (CCA) which also known as Beals syndrome or distal arthrogryposis type 9 (DA9). This antibody is specific to FBN2. It recognizes both two isoforms ~300 kDa and 160 kDa.
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