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Product Name
FCRL5 antibody
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Description
FCRL5 Rabbit Polyclonal antibody. Positive WB detected in Daudi cells, Raji cells. Observed molecular weight by Western-blot: 100 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
BXMAS1 antibody; CD307 antibody; DKFZp667E2019 antibody; DKFZp667F216 antibody; Fc receptor homolog 5 antibody; Fc receptor like 5 antibody; Fc receptor like protein 5 antibody; FcR like protein 5 antibody; FCRH5 antibody; FCRL5 antibody; FLJ00333 antibody; FLJ00397 antibody; IRTA2 antibody; PRO820 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of FCRL5 recombinant protein (Accession Number: NM_031281). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
Daudi cells were subjected to SDS PAGE followed by western blot with Catalog No:110604(FCRL5 Antibody) at dilution of 1:600
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Background
FCRL5, also known as CD307 or IRTA2, is a surface protein expressed selectively on B cells and plasma cells (PMID: 11290337). This protein has both an immunoreceptor tyrosine-based activation motif (ITAM)-like sequence and two consensus immunoreceptor tyrosine-based inhibitory motifs (ITIM) in its cytoplasmic region (PMID: 17522256). FCRL5 is implicated in B cell development and lymphomagenesis (PMID: 11290337; 11453668). It may have an immunoregulatory role in marginal zone B-cells.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"