FBXO9 antibody

Cat.#: 110560

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Product Information

  • Product Name
    FBXO9 antibody
  • Documents
  • Description
    FBXO9 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue. Positive WB detected in human liver tissue. Observed molecular weight by Western-blot: 52 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    dJ341E18.2 antibody; DKFZp434C0118 antibody; F box only protein 9 antibody; F box protein 9 antibody; FBX9 antibody; FBXO9 antibody; KIAA0936 antibody; NY REN 57 antibody; VCIA1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of FBXO9 recombinant protein (Accession Number: NM_033481). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:110560(FBXO9 antibody) at dilution of 1:300

    human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:110560(FBXO9 antibody) at dilution of 1:300

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:110560(FBXO9 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:110560(FBXO9 antibody) at dilution of 1:50 (under 10x lens)

  • Background
    F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins, and they are a family of eukaryotic proteins characterized by an approximately 40 amino acid motif. SCF complex, a class of ubiquitin ligases, consists of invariable components, Skp1 and Cullin, and variable components of F-box proteins, which have a primary role in determining substrate specificity. The F-box proteins are divided into 3 classes: FBWs containing WD-40 domains, FBLs containing leucine-rich repeats, and FBXs containing either different protein-protein interaction modules or no recognizable motifs. FBOX9 (or FBX9) belongs to the FBXs class, and 3 isoforms produced by alternative splicing has been described.

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